Meningioangiomatosis: A Disease With Many Radiological Faces

(D) High power (40×) demonstrating the neoplastic proliferation intermixed with residual brain cells such as cortical neurons (arrows). [...]patients with neurofibromatosis type 2–associated MA tend to remain asymptomatic throughout life.2-4 Histopathologically, the lesions contain a perivascular pr...

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Veröffentlicht in:Canadian journal of neurological sciences 2016-11, Vol.43 (6), p.847-849
Hauptverfasser: Nascimento, Fábio A., Kiehl, Tim-Rasmus, Tai, Peter C., Valiante, Taufik A., Krings, Timo
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Sprache:eng
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Zusammenfassung:(D) High power (40×) demonstrating the neoplastic proliferation intermixed with residual brain cells such as cortical neurons (arrows). [...]patients with neurofibromatosis type 2–associated MA tend to remain asymptomatic throughout life.2-4 Histopathologically, the lesions contain a perivascular proliferation of meningothelial and fibroblast-like cells, entrapped glial islands, and focal microcalcifications.4 In terms of neuroimaging, MA is fairly diverse in its presentation.5 Nonetheless, according to a recent study that reviewed imaging features of 101 previously published MA patients, there are a few radiological characteristics that are suggestive of this condition. [...]possible abnormalities include hypervascularity, abnormal vessels, and an avascular mass.5 MA is a difficult diagnosis to make, mainly because of nonspecific imaging findings. [...]we intend to remind clinicians to include MA in the differential diagnoses of intracortical lesions and medically refractory seizures, especially in young adults.
ISSN:0317-1671
2057-0155
DOI:10.1017/cjn.2016.292