Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit

Abstract Objective We explored how investigators of ongoing or planned trials respond to the publication of a trial stopped early for benefit addressing a similar question. Study Design and Setting We searched multiple databases from the date of publication of the truncated trial through August, 201...

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Veröffentlicht in:	Journal of clinical epidemiology 2017-02, Vol.82, p.12-19
Hauptverfasser:	Murad, M. Hassan, Guyatt, Gordon H, Domecq, Juan Pablo, Vernooij, Robin W.M, Erwin, Patricia J, Meerpohl, Joerg J, Prutsky, Gabriela J, Akl, Elie A, Mueller, Katharina, Bassler, Dirk, Schandelmaier, Stefan, Walter, Stephen D, Busse, Jason W, Kasenda, Benjamin, Pagano, Gennaro, Pardo-Hernandez, Hector, Montori, Victor M, Wang, Zhen, Briel, Matthias
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical trials Confidence intervals Databases, Factual - statistics & numerical data Decision making Early Termination of Clinical Trials Early termination of trials Epidemiologic Studies Epidemiology Funding Heart attacks Humans Insulin Intensive care Internal Medicine Intervention Methodology Mortality Patients Population Publishing - statistics & numerical data Randomized controlled trials Randomized Controlled Trials as Topic - statistics & numerical data Researchers Sepsis Studies Systematic review Trial design Trials stopped early for benefit
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