Mitochondrial dysfunction and oxidative stress in metabolic disorders — A step towards mitochondria based therapeutic strategies

Mitochondria are the powerhouses of the cell and are involved in essential functions of the cell, including ATP production, intracellular Ca2+ regulation, reactive oxygen species production & scavenging, regulation of apoptotic cell death and activation of the caspase family of proteases. Mitoch...

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Veröffentlicht in:	Biochimica et biophysica acta 2017-05, Vol.1863 (5), p.1066-1077
Hauptverfasser:	Bhatti, Jasvinder Singh, Bhatti, Gurjit Kaur, Reddy, P. Hemachandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular disease Metabolic syndrome Mitochondria Mitochondria-targeted antioxidants Obesity Oxidative stress Pre-diabetes Reactive oxygen species Type-2-diabetes
Online-Zugang:	Volltext
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