Nitroxides catalytically inhibit nitrite oxidation and heme inactivation induced by H2O2, nitrite and metmyoglobin or methemoglobin

Stable nitroxide radicals have multiple biological effects, although the mechanisms underlying them are not fully understood. Their protective effect against oxidative damage has been mainly attributed to scavenging deleterious radicals, oxidizing reduced metal ions and reducing oxyferryl centers of...

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Veröffentlicht in:	Free radical biology & medicine 2016-12, Vol.101, p.491-499
Hauptverfasser:	Samuni, Amram, Maimon, Eric, Goldstein, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalase-like activity EPR Heme protein Kinetics Mechanism Peroxidase-like activity Tyrosine nitration
Online-Zugang:	Volltext
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