Polyion complex micelles as vectors in gene therapy - pharmacokinetics and in vivo gene transfer

To establish non-viral gene delivery systems for intravenous administration, complexes of DNA and block copolymer consisting of poly-L-lysine and poly(ethylene glycol) were tested in in vivo turnover studies. The polyion complex micelles have self-assembling core-shell structures, yielding spherical...

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Veröffentlicht in:	Gene therapy 2002-03, Vol.9 (6), p.407-414
Hauptverfasser:	Harada-Shiba, M, Yamauchi, K, Harada, A, Takamisawa, I, Shimokado, K, Kataoka, K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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