Combination therapy with naltrexone and bupropion for obesity reduces total and visceral adiposity

The effects of combination naltrexone/bupropion therapy on body composition and visceral adipose tissue (VAT) mass were examined in a subset (n = 107) of obese subjects from a Phase 2 trial that compared the efficacy and safety of placebo, naltrexone monotherapy, bupropion monotherapy or one of thre...

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Veröffentlicht in:	Diabetes, obesity & metabolism obesity & metabolism, 2013-09, Vol.15 (9), p.863-866
Hauptverfasser:	Smith, S. R., Fujioka, K., Gupta, A. K., Billes, S. K., Burns, C., Kim, D., Dunayevich, E., Greenway, F. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Adipose tissue Adiposity - drug effects Analysis of Variance antiobesity drug Body composition Body Composition - drug effects Body fat Body weight loss Bupropion Bupropion - administration & dosage Bupropion - therapeutic use clinical trial Computed tomography Dopamine Uptake Inhibitors - administration & dosage Dopamine Uptake Inhibitors - therapeutic use Drug Therapy, Combination Female Humans Intra-Abdominal Fat - drug effects Male Middle Aged Naltrexone Naltrexone - administration & dosage Naltrexone - therapeutic use Obesity Obesity - drug therapy obesity therapy Placebos Tomography, X-Ray Computed Treatment Outcome Weight Loss - drug effects weight loss therapy
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