Homology Modeling Study of Bovine [mu]-Calpain Inhibitor-Binding Domains

The activated mammalian CAPN-structures, the CAPN/CAST complex in particular, have become an invaluable target model using the structure-based virtual screening of drug candidates from the discovery phase to development for over-activated CAPN linked to several diseases, such as post-ischemic injury...

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Veröffentlicht in:	International journal of molecular sciences 2014-05, Vol.15 (5), p.7897-7938
Hauptverfasser:	Chai, Han-Ha, Lim, Dajeong, Lee, Seung-Hwan, Chai, Hee-Yeoul, Jung, Eunkyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Cattle Enzymes Molecular biology Proteases
Online-Zugang:	Volltext
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