Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation: e0135519
Mesenchymal stem cell (MSC) differentiation is regulated by the extracellular matrix (ECM) through activation of intracellular signaling mediators. The stiffness of the ECM was shown to be an important regulatory factor for MSC differentiation, and transcriptional coactivator with PDZ-binding motif...
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Veröffentlicht in: | PloS one 2015-08, Vol.10 (8) |
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Hauptverfasser: | , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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