Disruption of Phosphoinositide-Specific Phospholipases C gamma 1 Contributes to Extracellular Matrix Synthesis of Human Osteoarthritis Chondrocytes

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation including extracellular matrix (ECM) degradation and cell loss. It is known that phosphoinositide-specific phospholipase gamma 1 (PLC gamma 1) can trigger several signaling pathways to regulate cell...

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Veröffentlicht in:	International journal of molecular sciences 2014-08, Vol.15 (8), p.13236-13246
Hauptverfasser:	Zeng, Guoqing, Cui, Xu, Liu, Zejun, Zhao, Honghai, Zheng, Xinpeng, Zhang, Bing, Xia, Chun
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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