Pharmacological effects of two cytolysins isolated from the sea anemone Stichodactyla helianthus

Sticholysins I and II (St I/II) are cytolysins purified from the sea anemone Stichodactyla helianthus . In this study, we show their pharmacological action on guinea-pig and snail models in native and pH-denatured conditions in order to correlate the pharmacological findings with the pore-forming ac...

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Veröffentlicht in:	Journal of biosciences 2009-12, Vol.34 (6), p.891-898
Hauptverfasser:	García, T., Martinez, D., Palmero, A., Soto, C., Tejuca, M., Pazos, F., Menéndez, R., Alvarez, C., Garateix, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Animals Biomedical and Life Sciences Biomedicine Cell Biology Cnidarian Venoms - isolation & purification Cnidarian Venoms - pharmacology Cytotoxins - isolation & purification Cytotoxins - pharmacology Erythrocytes - drug effects Guinea Pigs Heart Atria - drug effects Hemolysis - drug effects Life Sciences Marine Marine biology Microbiology Mollusca Mollusks Neurons - cytology Neurons - drug effects Neurons - physiology Organic Chemicals - isolation & purification Organic Chemicals - pharmacology Pharmacology Plant Sciences Pore Forming Cytotoxic Proteins - isolation & purification Pore Forming Cytotoxic Proteins - pharmacology Sea Anemones - chemistry Snails Stichodactyla helianthus Swine Zoology
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