Abstract 4058: DNA damage and tumour burden in mouse colon is increased in response to carcinogen exposure after induction of chronic inflammation - a more disease relevant model of colitis-associated colorectal cancer

Chronic inflammation (CI) such as inflammatory bowel disease increases the risk of developing colorectal cancer (CRC). Tumorigenesis is supported by inflammatory cytokines through increased cell proliferation and inhibiting apoptosis of neoplastic cells. The classic mouse model of colitis-associated...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.4058-4058
Hauptverfasser:	Lannagan, Tamsin RM, Mano, Mark T., Head, Richard J., Lockett, Trevor, Ernst, Matthias, Cosgrove, Leah J.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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