Diagnostic Performance of Cardiac Magnetic Resonance Imaging and Echocardiography in Evaluation of Cardiac and Paracardiac Masses
Echocardiography is the preferred initial imaging method for assessment of cardiac masses. Cardiac magnetic resonance (CMR) imaging, with its excellent tissue characterization and wide field of view, may provide additional unique information. We evaluated the predictive value of echocardiography and...
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| Veröffentlicht in: | The American journal of cardiology 2016, Vol.117 (1), p.135-140 |
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| container_title | The American journal of cardiology |
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| creator | Patel, Rima, MD Lim, Ruth P., MD Saric, Muhamed, MD Nayar, Ambika, MD Babb, James, PhD Ettel, Mark, MD Axel, Leon, MD, PhD Srichai, Monvadi B., MD |
| description | Echocardiography is the preferred initial imaging method for assessment of cardiac masses. Cardiac magnetic resonance (CMR) imaging, with its excellent tissue characterization and wide field of view, may provide additional unique information. We evaluated the predictive value of echocardiography and CMR imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. Fifty patients who underwent CMR evaluation of a cardiac mass with subsequent histopathologic diagnosis were identified. Echocardiography was available in 44 of 50 cases (88%). Echocardiographic and CMR characteristics were evaluated for predictive value in distinguishing tumor versus nontumor and malignant versus nonmalignant lesions using histopathology as the gold standard. The Wilcoxon rank-sum test was used to compare the 2 imaging methods' ability to provide the correct histopathologic diagnosis. Parameters associated with tumor included location outside the right atrium, T2 hyperintensity, and contrast enhancement. Parameters associated with malignancy included location outside the cardiac chambers, nonmobility, pericardial effusion, myocardial invasion, and contrast enhancement. CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77% vs 43%, p |
| doi_str_mv | 10.1016/j.amjcard.2015.10.014 |
| format | Article |
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Cardiac magnetic resonance (CMR) imaging, with its excellent tissue characterization and wide field of view, may provide additional unique information. We evaluated the predictive value of echocardiography and CMR imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. Fifty patients who underwent CMR evaluation of a cardiac mass with subsequent histopathologic diagnosis were identified. Echocardiography was available in 44 of 50 cases (88%). Echocardiographic and CMR characteristics were evaluated for predictive value in distinguishing tumor versus nontumor and malignant versus nonmalignant lesions using histopathology as the gold standard. The Wilcoxon rank-sum test was used to compare the 2 imaging methods' ability to provide the correct histopathologic diagnosis. Parameters associated with tumor included location outside the right atrium, T2 hyperintensity, and contrast enhancement. Parameters associated with malignancy included location outside the cardiac chambers, nonmobility, pericardial effusion, myocardial invasion, and contrast enhancement. CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77% vs 43%, p <0.0001). In conclusion, CMR offers the advantage of identifying paracardiac masses and providing crucial information on histopathology of cardiac masses.</description><identifier>ISSN: 0002-9149</identifier><identifier>EISSN: 1879-1913</identifier><identifier>DOI: 10.1016/j.amjcard.2015.10.014</identifier><identifier>PMID: 26552505</identifier><identifier>CODEN: AJCDAG</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Cardiovascular ; Diagnosis, Differential ; Echocardiography - methods ; Female ; Health Insurance Portability & Accountability Act 1996-US ; Heart Neoplasms - diagnosis ; Histopathology ; Humans ; Magnetic Resonance Imaging, Cine - methods ; Male ; Medical diagnosis ; Mens health ; Middle Aged ; Pathology ; Pericardial Effusion - diagnosis ; Predictive Value of Tests ; Reproducibility of Results ; Retrospective Studies ; Studies ; Tumors</subject><ispartof>The American journal of cardiology, 2016, Vol.117 (1), p.135-140</ispartof><rights>2016</rights><rights>Published by Elsevier Inc.</rights><rights>Copyright Elsevier Limited Jan 1, 2016</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c547t-78768bb39f3a7484b57a7f91660dcc3845ba7ee151066a69ffe6aef3428ab99d3</citedby><cites>FETCH-LOGICAL-c547t-78768bb39f3a7484b57a7f91660dcc3845ba7ee151066a69ffe6aef3428ab99d3</cites><orcidid>0000-0002-2842-5997 ; 0000-0002-0632-6373</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1753400525?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,4024,27923,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26552505$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Patel, Rima, MD</creatorcontrib><creatorcontrib>Lim, Ruth P., MD</creatorcontrib><creatorcontrib>Saric, Muhamed, MD</creatorcontrib><creatorcontrib>Nayar, Ambika, MD</creatorcontrib><creatorcontrib>Babb, James, PhD</creatorcontrib><creatorcontrib>Ettel, Mark, MD</creatorcontrib><creatorcontrib>Axel, Leon, MD, PhD</creatorcontrib><creatorcontrib>Srichai, Monvadi B., MD</creatorcontrib><title>Diagnostic Performance of Cardiac Magnetic Resonance Imaging and Echocardiography in Evaluation of Cardiac and Paracardiac Masses</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>Echocardiography is the preferred initial imaging method for assessment of cardiac masses. Cardiac magnetic resonance (CMR) imaging, with its excellent tissue characterization and wide field of view, may provide additional unique information. We evaluated the predictive value of echocardiography and CMR imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. Fifty patients who underwent CMR evaluation of a cardiac mass with subsequent histopathologic diagnosis were identified. Echocardiography was available in 44 of 50 cases (88%). Echocardiographic and CMR characteristics were evaluated for predictive value in distinguishing tumor versus nontumor and malignant versus nonmalignant lesions using histopathology as the gold standard. The Wilcoxon rank-sum test was used to compare the 2 imaging methods' ability to provide the correct histopathologic diagnosis. Parameters associated with tumor included location outside the right atrium, T2 hyperintensity, and contrast enhancement. Parameters associated with malignancy included location outside the cardiac chambers, nonmobility, pericardial effusion, myocardial invasion, and contrast enhancement. CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77% vs 43%, p <0.0001). In conclusion, CMR offers the advantage of identifying paracardiac masses and providing crucial information on histopathology of cardiac masses.</description><subject>Adult</subject><subject>Cardiovascular</subject><subject>Diagnosis, Differential</subject><subject>Echocardiography - methods</subject><subject>Female</subject><subject>Health Insurance Portability & Accountability Act 1996-US</subject><subject>Heart Neoplasms - diagnosis</subject><subject>Histopathology</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging, Cine - methods</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Mens health</subject><subject>Middle Aged</subject><subject>Pathology</subject><subject>Pericardial Effusion - diagnosis</subject><subject>Predictive Value of Tests</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>Studies</subject><subject>Tumors</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkk9v1DAQxSMEokvhI4AiceGSxY5jO76A0LJApSIq_pytiTPZeknsrZ1U2mO_eR12KaiXniyPf_NsvzdZ9pKSJSVUvN0uYdgaCO2yJJSn2pLQ6lG2oLVUBVWUPc4WhJCyULRSJ9mzGLdpSykXT7OTUnBecsIX2c1HCxvn42hNfoGh82EAZzD3Xb5K4hZM_jUBOJ9_x-jdn9OzATbWbXJwbb42l35-h_WbALvLfW5dvr6GfoLReve_0ExfQABzJxwjxufZkw76iC-O62n269P65-pLcf7t89nqw3lheCXHQtZS1E3DVMdAVnXVcAmyU1QI0hrD6oo3IBEpp0QIEKrrUAB2rCpraJRq2Wn25qC7C_5qwjjqwUaDfQ8O_RQ1rZlkjLBk3YOo5FSp2cuEvr6Hbv0UXPrITLGKkGR0oviBMsHHGLDTu2AHCHtNiZ7j1Ft9jFPPcc7lFGfqe3VUn5oB27uuv_kl4P0BwOTctcWgo7GYImptQDPq1tsHr3h3T8H01lkD_W_cY_z3Gx1LTfSPeabmkaKclCR5xW4BEujHzQ</recordid><startdate>2016</startdate><enddate>2016</enddate><creator>Patel, Rima, MD</creator><creator>Lim, Ruth P., MD</creator><creator>Saric, Muhamed, MD</creator><creator>Nayar, Ambika, MD</creator><creator>Babb, James, PhD</creator><creator>Ettel, Mark, MD</creator><creator>Axel, Leon, MD, PhD</creator><creator>Srichai, Monvadi B., MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7Z</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>7U7</scope><scope>C1K</scope><orcidid>https://orcid.org/0000-0002-2842-5997</orcidid><orcidid>https://orcid.org/0000-0002-0632-6373</orcidid></search><sort><creationdate>2016</creationdate><title>Diagnostic Performance of Cardiac Magnetic Resonance Imaging and Echocardiography in Evaluation of Cardiac and Paracardiac Masses</title><author>Patel, Rima, MD ; 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Cardiac magnetic resonance (CMR) imaging, with its excellent tissue characterization and wide field of view, may provide additional unique information. We evaluated the predictive value of echocardiography and CMR imaging parameters to identify tumors and malignancy and to provide histopathologic diagnosis of cardiac masses. Fifty patients who underwent CMR evaluation of a cardiac mass with subsequent histopathologic diagnosis were identified. Echocardiography was available in 44 of 50 cases (88%). Echocardiographic and CMR characteristics were evaluated for predictive value in distinguishing tumor versus nontumor and malignant versus nonmalignant lesions using histopathology as the gold standard. The Wilcoxon rank-sum test was used to compare the 2 imaging methods' ability to provide the correct histopathologic diagnosis. Parameters associated with tumor included location outside the right atrium, T2 hyperintensity, and contrast enhancement. Parameters associated with malignancy included location outside the cardiac chambers, nonmobility, pericardial effusion, myocardial invasion, and contrast enhancement. CMR identified 6 masses missed on transthoracic echocardiography (4 of which were outside the heart) and provided significantly more correct histopathologic diagnoses compared to echocardiography (77% vs 43%, p <0.0001). In conclusion, CMR offers the advantage of identifying paracardiac masses and providing crucial information on histopathology of cardiac masses.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26552505</pmid><doi>10.1016/j.amjcard.2015.10.014</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0002-2842-5997</orcidid><orcidid>https://orcid.org/0000-0002-0632-6373</orcidid></addata></record> |
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| subjects | Adult Cardiovascular Diagnosis, Differential Echocardiography - methods Female Health Insurance Portability & Accountability Act 1996-US Heart Neoplasms - diagnosis Histopathology Humans Magnetic Resonance Imaging, Cine - methods Male Medical diagnosis Mens health Middle Aged Pathology Pericardial Effusion - diagnosis Predictive Value of Tests Reproducibility of Results Retrospective Studies Studies Tumors |
| title | Diagnostic Performance of Cardiac Magnetic Resonance Imaging and Echocardiography in Evaluation of Cardiac and Paracardiac Masses |
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