Abstract 4565: Antizyme inhibitor regulates the expression of proteins involved in mitosis and affects prostate cancer cell growth

Upregulation of polyamine biosynthesis is a requirement for cell growth and proliferation. Increases in polyamine levels are mediated by the enzyme ornithine decarboxylase (ODC), which is inhibited by antizyme (AZ). Rescue of ODC activity is accomplished by expression of antizyme inhibitor (AZI), wh...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.4565-4565
Hauptverfasser:	Rice, James M., Kusztos, Amanda, Zetter, Bruce R.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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