Abstract LB-090: Sequence-based discovery of fully human anti-CD3 and anti-PDL1 single domain antibodies using novel transgenic rats

We have created a new platform and method for discovering fully human single domain antibodies (UniDabs) by combining novel transgenic rats (UniRats), antibody repertoire sequencing, and high-throughput gene assembly, expression and screening. UniRats express a comprehensive human VH gene repertoire...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.LB-090-LB-090
Hauptverfasser:	Trinklein, Nathan, Force Aldred, Shelley, Schellenberger, Ute, Harris, Kat, Clarke, Starlynn, Dang, Kevin, Pham, Duy, Bruggemann, Marianne, vanSchooten, Wim
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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