Novel imaging tools for investigating the role of immune signalling in the brain

Highlights • Traditional imaging modalities employed to visualise and interpret neuroimmune signalling are inadequate. • Tissue clearing facilitates the 3-dimensional imaging of organs. • Nanoparticles have a superior luminescence signal, stability and reduces background noise compared to fluorophor...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2016-11, Vol.58, p.40-47
Hauptverfasser:	Jacobsen, Jonathan Henry W, Parker, Lindsay M, Everest-Dass, Arun V, Schartner, Erik P, Tsiminis, Georgios, Staikopoulos, Vasiliki, Hutchinson, Mark R, Mustafa, Sanam
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Brain - diagnostic imaging Brain - immunology Encephalitis - diagnostic imaging Encephalitis - immunology Humans Imaging tools Immune signalling Immunohistochemistry MALDI imaging Nanoparticles Nanoparticles - administration & dosage Neuroimaging - methods Neuroinflammation Psychiatry Raman spectroscopy RNA-based probes Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tissue clearing
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