Novel insights into esophageal diagnostic procedures

The 21st century offers new advances in diagnostic procedures and protocols in the management of esophageal diseases. This review highlights the most recent advances in esophageal diagnostic technologies, including clinical applications of novel endoscopic devices, such as ultrathin endoscopy and co...

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Veröffentlicht in:Annals of the New York Academy of Sciences 2016-09, Vol.1380 (1), p.162-177
Hauptverfasser: Savarino, Edoardo, Ottonello, Andrea, Tolone, Salvatore, Bartolo, Ottavia, Baeg, Myong Ki, Farjah, Farhood, Kuribayashi, Shiko, Shetler, Katerina P., Lottrup, Christian, Stein, Ellen
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container_title Annals of the New York Academy of Sciences
container_volume 1380
creator Savarino, Edoardo
Ottonello, Andrea
Tolone, Salvatore
Bartolo, Ottavia
Baeg, Myong Ki
Farjah, Farhood
Kuribayashi, Shiko
Shetler, Katerina P.
Lottrup, Christian
Stein, Ellen
description The 21st century offers new advances in diagnostic procedures and protocols in the management of esophageal diseases. This review highlights the most recent advances in esophageal diagnostic technologies, including clinical applications of novel endoscopic devices, such as ultrathin endoscopy and confocal laser endomicroscopy for diagnosis and management of Barrett's esophagus; novel parameters and protocols in high‐resolution esophageal manometry for the identification and better classification of motility abnormalities; innovative connections between esophageal motility disorder diagnosis and detection of gastroesophageal reflux disease (GERD); impedance–pH testing for detecting the various GERD phenotypes; performance of distensibility testing for better pathophysiological knowledge of the esophagus and other gastrointestinal abnormalities; and a modern view of positron emission tomography scanning in metastatic disease detection in the era of accountability as a model for examining other new technologies. We now have better tools than ever for the detection of esophageal diseases and disorders, and emerging data are helping to define how well these tools change management and provide value to clinicians. This review features novel insights from multidisciplinary perspectives, including both surgical and medical perspectives, into these new tools, and it offers guidance on the use of novel technologies in clinical practice and future directions for research.
doi_str_mv 10.1111/nyas.13255
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subjects cancer staging
Diagnostic tests
distensibility
Esophageal Motility Disorders - diagnosis
Esophageal Motility Disorders - physiopathology
Esophageal pH Monitoring - methods
Esophageal pH Monitoring - trends
Esophagoscopy - methods
Esophagoscopy - trends
Esophagus
Gastroesophageal reflux
Gastroesophageal Reflux - diagnosis
Gastroesophageal Reflux - physiopathology
GERD
high-resolution esophageal manometry
Humans
impedance
Manometry - methods
Manometry - trends
Motility
positron emission tomography
title Novel insights into esophageal diagnostic procedures
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