Protection of a novel epitope-RNA VLP double-effective VLP vaccine for foot-and-mouth disease

Foot and mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals. Previously, we found that the epitope peptide EP141-160 displayed on virus-like particles (VLP) for use as a vaccine showed high immunoreactivity and conferred partially effective protection to animals. In th...

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Veröffentlicht in:	Antiviral research 2016-10, Vol.134, p.108-116
Hauptverfasser:	Dong, Yan-mei, Cai, Jian-chun, Chen, Hao-tai, Chen, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - immunology Blotting, Western Enzyme-Linked Immunosorbent Assay Epitope-RNA Epitopes - genetics Epitopes - immunology Foot-and-Mouth Disease - immunology Foot-and-Mouth Disease - prevention & control Foot-and-Mouth Disease - virology Foot-and-mouth disease virus Foot-and-Mouth Disease Virus - genetics Foot-and-Mouth Disease Virus - immunology Guinea Pigs Mice Neutralization Tests Picornaviridae Potency RNA, Antisense - genetics RNA, Viral - immunology Swine Swine Diseases - immunology Swine Diseases - prevention & control Vaccine Potency Vaccines, Virus-Like Particle - administration & dosage Vaccines, Virus-Like Particle - immunology
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