Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats

alpha-Glycosyl isoquercitrin (AGIQ) is highly absorbable and has been shown to possess antioxidative properties. Based on a favorable safety profile, it has been confirmed as generally recognized as safe (GRAS) compound by the FDA. Nevertheless, safety and toxicity information for AGIQ is still spar...

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Veröffentlicht in:	Food and chemical toxicology 2016-11, Vol.97, p.354-366
Hauptverfasser:	Nyska, Abraham, Hayashi, Shim-mo, Koyanagi, Mihoko, Davis, Jeffrey P., Jokinen, Micheal P., Ramot, Yuval, Maronpot, Robert R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral AGIQ Alpha-glycosyl isoquercitrin Animals Body Weight - drug effects Dose-Response Relationship, Drug EMIQ Female Flavonol Glycosides - chemistry Glycosides - toxicity Hematologic Tests Isoquercitrin Male Motor Activity - drug effects Organ Size - drug effects Quercetin Quercetin - analogs & derivatives Quercetin - chemistry Quercetin - toxicity Rats Rats, Sprague-Dawley Safety Sprague-Dawley Toxicity Toxicokinetics
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