Improved Pharmacokinetics Following PEGylation and Dimerization of a c(RGD-ACH-K) Conjugate Used for Tumor Positron Emission Tomography Imaging

Improving the in vivo pharmacokinetics (PK) of positron emission tomography (PET) radiotracers is of critical importance to tumor diagnosis and therapy. In the case of peptide-based radiotracers, the modification and addition of a linker or spacer functional group often offer faster in vivo pharmaco...

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Veröffentlicht in:Cancer biotherapy & radiopharmaceuticals 2016-10, Vol.31 (8), p.295-301
Hauptverfasser: Lee, Ji Woong, Lee, Yong Jin, Shin, Un Chol, Kim, Suhng Wook, Kim, Byung Il, Lee, Kyo Chul, Kim, Jung Young, Park, Ji-Ae
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Sprache:eng
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