The Effects of Chlormequat Chloride on the Development of Pubertal Male Rats

[Display omitted] •The developmental toxicity of Chlormequat Chloride was studied.•Chlormequat Chloride impacted the width of growth plates.•Chlormequat Chloride decreased the concentration of GH in serum.•Chlormequat Chloride inhibited the mRNA expression of GH, GHR and IGF-I. Chlormequat Chloride...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2016-10, Vol.47, p.92-99
Hauptverfasser:	Huang, Dan, Wu, Shuang, Pan, Yao, Meng, Qinghe, Chu, Hongqian, Jiang, Jianjun, Shang, Lanqin, Hao, Weidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - blood Animals Body weight Body Weight - drug effects Chloride Chlorides Chlormequat - toxicity Chlormequat chloride Developmental toxicity Emergency Femur Gene expression Gene Expression Regulation - drug effects Growth hormone Growth Hormone - blood Growth Hormone - genetics Growth Plate - drug effects Growth regulators Insulin Insulin-like growth factor 1 Insulin-Like Growth Factor I - analysis Insulin-Like Growth Factor I - genetics Male Organ Size - drug effects Phytohormones Plant growth Plant Growth Regulators - toxicity Puberty - drug effects Rats Rats, Sprague-Dawley Receptors, Somatotropin - genetics Rodents Toxicity
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