Early diaphragm pacing in patients with amyotrophic lateral sclerosis (RespiStimALS): a randomised controlled triple-blind trial

Summary Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated with respiratory muscle weakness and respiratory failure. Non-invasive ventilation alleviates respiratory symptoms and prolongs life, but is a palliative intervention. Slowing the deterioration of diaph...

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Veröffentlicht in:	Lancet neurology 2016-11, Vol.15 (12), p.1217-1227
Hauptverfasser:	Gonzalez-Bermejo, Jésus, Dr, Morélot-Panzini, Capucine, MD, Tanguy, Marie-Laure, PharmD, Meininger, Vincent, Prof, Pradat, Pierre-François, MD, Lenglet, Timothée, MD, Bruneteau, Gaëlle, MD, Forestier, Nadine Le, MD, Couratier, Philippe, Prof, Guy, Nathalie, MD, Desnuelle, Claude, Prof, Prigent, Hélène, MD, Perrin, Christophe, MD, Attali, Valérie, MD, Fargeot, Catherine, PharmD, Nierat, Marie-Cécile, PhD, Royer, Catherine, MD, Ménégaux, Fabrice, Prof, Salachas, François, MD, Similowski, Thomas, Prof
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - complications Amyotrophic Lateral Sclerosis - therapy Diaphragm - innervation Diaphragm - physiopathology Double-Blind Method Early Termination of Clinical Trials Electric Stimulation Therapy - adverse effects Electric Stimulation Therapy - methods Female Humans Laparoscopy Male Middle Aged Mortality Neurology Ostomy Palliative care Phrenic Nerve Respiration Disorders Respiration, Artificial Respiratory Insufficiency - prevention & control Surgery Ventilation
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