The biochemistry and cell biology of aging: metabolic regulation through mitochondrial signaling

Cellular and organ metabolism affects organismal lifespan. Aging is characterized by increased risks for metabolic disorders, with age-associated degenerative diseases exhibiting varying degrees of mitochondrial dysfunction. The traditional view of the role of mitochondria generated reactive oxygen...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2014-03, Vol.306 (6), p.E581-E591
Hauptverfasser:	Long, Yun Chau, Tan, Theresa May Chin, Takao, Inoue, Tang, Bor Luen
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - metabolism Animals Biochemistry Cellular biology Endocrinology Epigenesis, Genetic Humans Longevity Metabolic Diseases - etiology Metabolic Diseases - metabolism Metabolic Diseases - prevention & control Metabolism Mitochondria Mitochondria - metabolism Models, Biological Oxidative Stress Signal Transduction
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