SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia

Background. Solithromycin, a novel macrolide antibiotic with both intravenous and oral formulations dosed once daily, has completed 2 global phase 3 trials for treatment of community-acquired bacterial pneumonia. Methods. A total of 863 adults with community-acquired bacterial pneumonia (Pneumonia O...

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Veröffentlicht in:	Clinical infectious diseases 2016-10, Vol.63 (8), p.1007-1016
Hauptverfasser:	File, Thomas M., Rewerska, Barbara, Vucinić-Mihailović, Violeta, Gonong, Joven Roque V., Das, Anita F., Keedy, Kara, Taylor, David, Sheets, Amanda, Fernandes, Prabhavathi, Oldach, David, Jamieson, Brian D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Administration, Oral Adult Aged Aged, 80 and over Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - adverse effects Antibiotics ARTICLES AND COMMENTARIES Bacteria Community-Acquired Infections - diagnosis Community-Acquired Infections - drug therapy Community-Acquired Infections - microbiology Comorbidity Comparative analysis Drug Resistance, Bacterial Female Fluoroquinolones - administration & dosage Fluoroquinolones - adverse effects Humans Macrolides - administration & dosage Macrolides - adverse effects Male Medical treatment Microbial Sensitivity Tests Middle Aged Pneumonia Pneumonia, Bacterial - diagnosis Pneumonia, Bacterial - drug therapy Pneumonia, Bacterial - microbiology Treatment Outcome Triazoles - administration & dosage Triazoles - adverse effects
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