Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules
A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a sur...
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Veröffentlicht in: | Lung 2015-12, Vol.193 (6), p.1051-1054 |
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creator | Pietrangeli, V. Piciucchi, S. Tomassetti, S. Ravaglia, C. Gurioli, C. Gurioli, Ch Cavazza, A. Dubini, A. Poletti, V. |
description | A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered. |
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CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.</description><identifier>ISSN: 0341-2040</identifier><identifier>EISSN: 1432-1750</identifier><identifier>DOI: 10.1007/s00408-015-9817-4</identifier><identifier>PMID: 26446675</identifier><identifier>CODEN: LUNGD9</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Aged ; Bronchiolitis Obliterans - complications ; Bronchiolitis Obliterans - diagnosis ; Cough - etiology ; Dyspnea - etiology ; Epidemiology ; Female ; Headaches ; Humans ; Hyperplasia - diagnosis ; Idiopathic Pulmonary Fibrosis - complications ; Idiopathic Pulmonary Fibrosis - diagnosis ; Lung - diagnostic imaging ; Lung - pathology ; Lung diseases ; Medicine ; Medicine & Public Health ; Multiple Pulmonary Nodules - complications ; Multiple Pulmonary Nodules - diagnosis ; Neuroendocrine Cells - pathology ; Pneumology/Respiratory System ; Pneumonia ; Tomography, X-Ray Computed</subject><ispartof>Lung, 2015-12, Vol.193 (6), p.1051-1054</ispartof><rights>Springer Science+Business Media New York 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-abf9513ac6e308018952418c8db643c0ada624c2bc40c862c9bd4c81c82266e03</citedby><cites>FETCH-LOGICAL-c475t-abf9513ac6e308018952418c8db643c0ada624c2bc40c862c9bd4c81c82266e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00408-015-9817-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00408-015-9817-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26446675$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pietrangeli, V.</creatorcontrib><creatorcontrib>Piciucchi, S.</creatorcontrib><creatorcontrib>Tomassetti, S.</creatorcontrib><creatorcontrib>Ravaglia, C.</creatorcontrib><creatorcontrib>Gurioli, C.</creatorcontrib><creatorcontrib>Gurioli, Ch</creatorcontrib><creatorcontrib>Cavazza, A.</creatorcontrib><creatorcontrib>Dubini, A.</creatorcontrib><creatorcontrib>Poletti, V.</creatorcontrib><title>Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules</title><title>Lung</title><addtitle>Lung</addtitle><addtitle>Lung</addtitle><description>A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.</description><subject>Aged</subject><subject>Bronchiolitis Obliterans - complications</subject><subject>Bronchiolitis Obliterans - diagnosis</subject><subject>Cough - etiology</subject><subject>Dyspnea - etiology</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Headaches</subject><subject>Humans</subject><subject>Hyperplasia - diagnosis</subject><subject>Idiopathic Pulmonary Fibrosis - complications</subject><subject>Idiopathic Pulmonary Fibrosis - diagnosis</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - pathology</subject><subject>Lung diseases</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Multiple Pulmonary Nodules - complications</subject><subject>Multiple Pulmonary Nodules - diagnosis</subject><subject>Neuroendocrine Cells - pathology</subject><subject>Pneumology/Respiratory System</subject><subject>Pneumonia</subject><subject>Tomography, X-Ray Computed</subject><issn>0341-2040</issn><issn>1432-1750</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkc1u1DAUhS0EokPhAdggS2zYBHz9Fw-7tvxMpartgllHjnPDuMo4gx2DuutLsIOX65PgIQUhJMTq6l5_5xxZh5CnwF4CY_WrxJhkpmKgqqWBupL3yAKk4BXUit0nCyYkVLwwB-RRSleMQa1BPSQHXEupda0W5Osb3_c5IT3HHEcM3eiiD0hX1zuMu8Emb-kXP23oRTv4CaOd_Gekx3EMbuPHcvKJ2tDRdcp2oKehIGkq17JcBszbMXj7mh4Fug75J3J7822FtnMbxJJ6aaeiCLc33-eU87HLA6bH5EFvh4RP7uYhWb97--FkVZ1dvD89OTqrnKzVVNm2XyoQ1mkUzDAwS8UlGGe6VkvhmO2s5tLx1knmjOZu2XbSGXCGc62RiUPyYvbdxfFTxjQ1W58cDoMNOObUgBG1AAF6-X-0FkoIxY0u6PO_0Ksxx1A-sqckKDByT8FMuTimFLFvdtFvbbxugDX7epu53qbU2-zrbWTRPLtzzu0Wu9-KX30WgM9AKk_hI8Y_ov_p-gNhlbNH</recordid><startdate>20151201</startdate><enddate>20151201</enddate><creator>Pietrangeli, V.</creator><creator>Piciucchi, S.</creator><creator>Tomassetti, S.</creator><creator>Ravaglia, C.</creator><creator>Gurioli, C.</creator><creator>Gurioli, Ch</creator><creator>Cavazza, A.</creator><creator>Dubini, A.</creator><creator>Poletti, V.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20151201</creationdate><title>Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules</title><author>Pietrangeli, V. ; Piciucchi, S. ; Tomassetti, S. ; Ravaglia, C. ; Gurioli, C. ; Gurioli, Ch ; Cavazza, A. ; Dubini, A. ; Poletti, V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-abf9513ac6e308018952418c8db643c0ada624c2bc40c862c9bd4c81c82266e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Aged</topic><topic>Bronchiolitis Obliterans - complications</topic><topic>Bronchiolitis Obliterans - diagnosis</topic><topic>Cough - etiology</topic><topic>Dyspnea - etiology</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Headaches</topic><topic>Humans</topic><topic>Hyperplasia - diagnosis</topic><topic>Idiopathic Pulmonary Fibrosis - complications</topic><topic>Idiopathic Pulmonary Fibrosis - diagnosis</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - pathology</topic><topic>Lung diseases</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Multiple Pulmonary Nodules - complications</topic><topic>Multiple Pulmonary Nodules - diagnosis</topic><topic>Neuroendocrine Cells - pathology</topic><topic>Pneumology/Respiratory System</topic><topic>Pneumonia</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pietrangeli, V.</creatorcontrib><creatorcontrib>Piciucchi, S.</creatorcontrib><creatorcontrib>Tomassetti, S.</creatorcontrib><creatorcontrib>Ravaglia, C.</creatorcontrib><creatorcontrib>Gurioli, C.</creatorcontrib><creatorcontrib>Gurioli, Ch</creatorcontrib><creatorcontrib>Cavazza, A.</creatorcontrib><creatorcontrib>Dubini, A.</creatorcontrib><creatorcontrib>Poletti, V.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Lung</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pietrangeli, V.</au><au>Piciucchi, S.</au><au>Tomassetti, S.</au><au>Ravaglia, C.</au><au>Gurioli, C.</au><au>Gurioli, Ch</au><au>Cavazza, A.</au><au>Dubini, A.</au><au>Poletti, V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules</atitle><jtitle>Lung</jtitle><stitle>Lung</stitle><addtitle>Lung</addtitle><date>2015-12-01</date><risdate>2015</risdate><volume>193</volume><issue>6</issue><spage>1051</spage><epage>1054</epage><pages>1051-1054</pages><issn>0341-2040</issn><eissn>1432-1750</eissn><coden>LUNGD9</coden><abstract>A 74-year-old non-smoker female presented to our attention with a history of dyspnea and cough. CT scan revealed multiple areas of patchy ground glass attenuation associated to a diffuse mosaic oligoemia. Scattered bilateral subcentimetric pulmonary nodules were also present. Patient underwent a surgical lung biopsy. Specimens showed features of diffuse neuroendocrine hyperplasia, microhoneycombing, fibroblast foci. A final diagnosis of diffuse neuroendocrine hyperplasia with obliterative bronchiolitis and UIP was rendered.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>26446675</pmid><doi>10.1007/s00408-015-9817-4</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Bronchiolitis Obliterans - complications Bronchiolitis Obliterans - diagnosis Cough - etiology Dyspnea - etiology Epidemiology Female Headaches Humans Hyperplasia - diagnosis Idiopathic Pulmonary Fibrosis - complications Idiopathic Pulmonary Fibrosis - diagnosis Lung - diagnostic imaging Lung - pathology Lung diseases Medicine Medicine & Public Health Multiple Pulmonary Nodules - complications Multiple Pulmonary Nodules - diagnosis Neuroendocrine Cells - pathology Pneumology/Respiratory System Pneumonia Tomography, X-Ray Computed |
title | Diffuse Neuroendocrine Hyperplasia with Obliterative Bronchiolitis and Usual Interstitial Pneumonia: An Unusual “Headcheese Pattern” with Nodules |
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