Abstract LB-165: Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma

The let-7 microRNA family are known tumor suppressors often deregulated in cancer, yet the underlying mechanisms of let-7 disruption remain poorly understood. Neuroblastoma, a neural crest derived tumor, is defined in part by poor prognosis associated with genetic amplification of MYCN, itself a let...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.LB-165-LB-165
Hauptverfasser:	Powers, John T., Tsanov, Kaloyan, Roels, Frederik, Spina, Catherine, Ebright, Richard, Seligson, Marc, de Soysa, Yvanka, Cahan, Patrick, Pearson, Daniel, Theißen, Jessica, Tu, Ho-Chou, LaPier, Grace, Osborne, Jihan, Ross, Samantha, Collins, James, Berthold, Frank, Daley, George
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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