Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice

Inflammatory events during experimental colitis induced by DSS. Inflammatory bowel disease (IBD) affects millions of people worldwide but its pathophysiology remains unclear. Therefore, experimental models of colitis have contributed crucially for the understanding of IBD, and also in the investigat...

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Veröffentlicht in:	Biochemical pharmacology 2012-12, Vol.84 (11), p.1459-1469
Hauptverfasser:	Bento, Allisson Freire, Leite, Daniela Ferraz Pereira, Marcon, Rodrigo, Claudino, Rafaela Franco, Dutra, Rafael Cypriano, Cola, Maíra, Martini, Alessandra Cadete, Calixto, João B.
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion Animals biomarkers Blotting, Western Cell influx chemokines Chronic inflammation Colitis dextran Dextran sodium sulfate Dextran Sulfate - administration & dosage digestive system disease course Gastroenteritis - immunology Gastroenteritis - prevention & control inflammation Inflammatory mediators interleukin-10 interleukin-4 Male Mice Mice, Inbred BALB C necrosis pathophysiology people pharmacology prostaglandin synthase Real-Time Polymerase Chain Reaction sodium sulfate
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