Immunostimulatory role of mitochondrial DAMPs: alarming for pre-eclampsia?

Mitochondria are critical signaling organelles that play an integral cellular role in the activation of diverse physiological responses to perturbation. Mitochondrial damage‐associated molecular patterns (DAMPs) act as redox signaling nodes synchronizing mitochondrial metabolism with triggering of i...

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Veröffentlicht in:	American journal of reproductive immunology (1989) 2016-11, Vol.76 (5), p.341-347
Hauptverfasser:	McCarthy, Cathal Michael, Kenny, Louise Clare
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals damage-associated molecular patterns Female Humans Immunity, Innate Immunization Inflammation - immunology innate immune response Mitochondria - immunology Mitochondria - metabolism Mitochondrial DNA mitochondrial dysfunction Oxidative Stress Pre-Eclampsia - immunology Preeclampsia Pregnancy Receptors, Pattern Recognition - metabolism redox signals Rodents Signal Transduction
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