Abstract 3099: KRAS and clinical context: Differential dynamic signaling output of KRAS mutant lung, colorectal and pancreatic cancer cell lines when exposed to targeted anticancer drugs

Background Clinical trials have shown that cancers originating from different tissues driven by the same oncogene respond differently to targeted anticancer drugs. We aimed to understand different signaling patterns in KRAS mutant cells derived from non-small cell lung cancer (NSCLC), colorectal can...

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Veröffentlicht in:Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.3099-3099
Hauptverfasser: Stewart, Adam, Coker, Elizabeth, Minchom, Anna, Thavasu, Parames, Georgiou, Alexandros, Sadanandam, Anguraj, Yap, Timothy A., de Bono, Johann S., Al-Lazikani, Bissan, Banerji, Udai
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Sprache:eng
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