Abstract 229: A metabolic switch controls cell fate decision-making in intestinal differentiation downstream of the tumor suppressor adenomatous polyposis coli (apc)

Mutation in the tumor suppressor Adenomatous Polyposis Coli (APC) is the primary initiating mutation in a majority of colon tumors. Recent studies have shown that APC positively correlates with Mitochondrial Pyruvate Carrier 1 (MPC1), a crucial player in pyruvate metabolism and has been reported to...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2016-07, Vol.76 (14_Supplement), p.229-229
Hauptverfasser:	Sandoval, Imelda T., Delacruz, Richard Glenn C., Miller, Braden N., Satterfield, Christeena, Olson, Kristophor, Hill, Shauna, Van Remmen, Holly, Rutter, Jared, Jones, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Danio rerio
Online-Zugang:	Volltext
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