Metabolic study of enrofloxacin and metabolic profile modifications in broiler chicken tissues after drug administration

•Identification of new metabolites from enrofloxacin in chicken tissues by LC–HRMS.•Distribution of enrofloxacin and their metabolites in chicken tissues.•Classification of medicated chicken samples by PCA and PLS-DA.•Tentative identification of markers from medicated chicken tissue samples. In this...

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Veröffentlicht in:	Food chemistry 2015-04, Vol.172, p.30-39
Hauptverfasser:	Morales-Gutiérrez, F.J., Barbosa, J., Barrón, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics Chicken tissues Chickens - metabolism Enrofloxacin Fluoroquinolones - administration & dosage Fluoroquinolones - pharmacokinetics Liver - chemistry Liver - metabolism Metabolic profile Metabolites Metabolomics Multivariate data analyses Muscles - chemistry Muscles - metabolism
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