Effects of heat-treatment on surface morphologies, mechanical properties of nanofibrous poly(propylene carbonate) biocomposites and its cell culture
[Display omitted] •PPC nanofibers exhibited soft rubber-like features.•Mechanics of PPC nanofibers were dramatically improved after heat-treatment.•PPC/PLA composite nanofibers showed topographically peculiar morphologies.•Biomedical applications as a scaffold tissue engineering. We report controlle...
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| Veröffentlicht in: | Colloids and surfaces. A, Physicochemical and engineering aspects Physicochemical and engineering aspects, 2016-03, Vol.492, p.138-143 |
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| container_title | Colloids and surfaces. A, Physicochemical and engineering aspects |
| container_volume | 492 |
| creator | Park, Ji-young Lee, Eun-Sook Amna, Touseef Jang, Yeonju Park, Dong Hyup Kim, Byoung-Suhk |
| description | [Display omitted]
•PPC nanofibers exhibited soft rubber-like features.•Mechanics of PPC nanofibers were dramatically improved after heat-treatment.•PPC/PLA composite nanofibers showed topographically peculiar morphologies.•Biomedical applications as a scaffold tissue engineering.
We report controlled surface morphologies, mechanical properties and cell culture of biomimetic pure poly(propylene carbonate) (PPC) and PPC/poly(lactic acid) (PLA) composite nanofibers prepared by sol–gel electrospinning. Pure PPC nanofibers exhibited soft rubber-like features with lower mechanical properties (elastic modulus ∼59.7MPa, tensile strength ∼6.2MPa), while the mechanical properties of as-spun PPC nanofibers were dramatically improved after heat-treatments at 60°C. Furthermore, the PPC/PLA composite nanofibers exhibited topographically peculiar morphologies (in particular, an embossing-like surface protrusions), probably due to poor miscibility between PPC and PLA. CCK-8 assay results of cultured myoblasts clarified that pure PPC and PPC/PLA composite nanofibers were nontoxic to the cells, which therefore, suggest them to be used in biomedical applications as a scaffold for tissue engineering. |
| doi_str_mv | 10.1016/j.colsurfa.2015.11.075 |
| format | Article |
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•PPC nanofibers exhibited soft rubber-like features.•Mechanics of PPC nanofibers were dramatically improved after heat-treatment.•PPC/PLA composite nanofibers showed topographically peculiar morphologies.•Biomedical applications as a scaffold tissue engineering.
We report controlled surface morphologies, mechanical properties and cell culture of biomimetic pure poly(propylene carbonate) (PPC) and PPC/poly(lactic acid) (PLA) composite nanofibers prepared by sol–gel electrospinning. Pure PPC nanofibers exhibited soft rubber-like features with lower mechanical properties (elastic modulus ∼59.7MPa, tensile strength ∼6.2MPa), while the mechanical properties of as-spun PPC nanofibers were dramatically improved after heat-treatments at 60°C. Furthermore, the PPC/PLA composite nanofibers exhibited topographically peculiar morphologies (in particular, an embossing-like surface protrusions), probably due to poor miscibility between PPC and PLA. CCK-8 assay results of cultured myoblasts clarified that pure PPC and PPC/PLA composite nanofibers were nontoxic to the cells, which therefore, suggest them to be used in biomedical applications as a scaffold for tissue engineering.</description><identifier>ISSN: 0927-7757</identifier><identifier>EISSN: 1873-4359</identifier><identifier>DOI: 10.1016/j.colsurfa.2015.11.075</identifier><language>eng</language><publisher>Elsevier B.V</publisher><subject>Biocomposite ; Biotechnology ; Carbonates ; Cell culture ; Electrospinning ; Heat treatment ; Mechanical properties ; Mechanical property ; Morphology ; Nanofiber ; Nanofibers ; Nanostructure ; Poly(propylene carbonate)</subject><ispartof>Colloids and surfaces. A, Physicochemical and engineering aspects, 2016-03, Vol.492, p.138-143</ispartof><rights>2015 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-118e67fb95d0e96f70752805858c691458c0768653fa7280622598609d4449a3</citedby><cites>FETCH-LOGICAL-c415t-118e67fb95d0e96f70752805858c691458c0768653fa7280622598609d4449a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0927775715303794$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids></links><search><creatorcontrib>Park, Ji-young</creatorcontrib><creatorcontrib>Lee, Eun-Sook</creatorcontrib><creatorcontrib>Amna, Touseef</creatorcontrib><creatorcontrib>Jang, Yeonju</creatorcontrib><creatorcontrib>Park, Dong Hyup</creatorcontrib><creatorcontrib>Kim, Byoung-Suhk</creatorcontrib><title>Effects of heat-treatment on surface morphologies, mechanical properties of nanofibrous poly(propylene carbonate) biocomposites and its cell culture</title><title>Colloids and surfaces. A, Physicochemical and engineering aspects</title><description>[Display omitted]
•PPC nanofibers exhibited soft rubber-like features.•Mechanics of PPC nanofibers were dramatically improved after heat-treatment.•PPC/PLA composite nanofibers showed topographically peculiar morphologies.•Biomedical applications as a scaffold tissue engineering.
We report controlled surface morphologies, mechanical properties and cell culture of biomimetic pure poly(propylene carbonate) (PPC) and PPC/poly(lactic acid) (PLA) composite nanofibers prepared by sol–gel electrospinning. Pure PPC nanofibers exhibited soft rubber-like features with lower mechanical properties (elastic modulus ∼59.7MPa, tensile strength ∼6.2MPa), while the mechanical properties of as-spun PPC nanofibers were dramatically improved after heat-treatments at 60°C. Furthermore, the PPC/PLA composite nanofibers exhibited topographically peculiar morphologies (in particular, an embossing-like surface protrusions), probably due to poor miscibility between PPC and PLA. CCK-8 assay results of cultured myoblasts clarified that pure PPC and PPC/PLA composite nanofibers were nontoxic to the cells, which therefore, suggest them to be used in biomedical applications as a scaffold for tissue engineering.</description><subject>Biocomposite</subject><subject>Biotechnology</subject><subject>Carbonates</subject><subject>Cell culture</subject><subject>Electrospinning</subject><subject>Heat treatment</subject><subject>Mechanical properties</subject><subject>Mechanical property</subject><subject>Morphology</subject><subject>Nanofiber</subject><subject>Nanofibers</subject><subject>Nanostructure</subject><subject>Poly(propylene carbonate)</subject><issn>0927-7757</issn><issn>1873-4359</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFUU2LFDEUDKLguPoXJMcV7Dbp7nzdlGX9gAUvew-Z9IuTIZ20SVqY_-EPNu3oeS95kFdVr4pC6C0lPSWUfzj3NoWyZWf6gVDWU9oTwZ6hA5Vi7KaRqefoQNQgOiGYeIlelXImhExMqAP6fe8c2FpwcvgEpnY1t3eBWHGK-K-qBbykvJ5SSD88lPd4AXsy0VsT8JrTCrm2710gmpicP-a0FbymcLnd15cAEbA1-ZiiqfAOH32yaVlT8bXRTJyxb_cthIDtFuqW4TV64Uwo8ObfvEGPn-8f7752D9-_fLv79NDZibLaUSqBC3dUbCaguBMt9iAJk0xarujUBhFccjY6I9qCDwNTkhM1T9OkzHiDbq-yzebPDUrViy-7DxOhRdBUjmJQjHL-NFSocWiiXDYov0JtTqVkcHrNfjH5oinRe2H6rP8XpvfCNKW6OW_Ej1citMi_PGRdrIdoYfa5VaTn5J-S-AOnB6Sf</recordid><startdate>20160305</startdate><enddate>20160305</enddate><creator>Park, Ji-young</creator><creator>Lee, Eun-Sook</creator><creator>Amna, Touseef</creator><creator>Jang, Yeonju</creator><creator>Park, Dong Hyup</creator><creator>Kim, Byoung-Suhk</creator><general>Elsevier B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope><scope>7QO</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20160305</creationdate><title>Effects of heat-treatment on surface morphologies, mechanical properties of nanofibrous poly(propylene carbonate) biocomposites and its cell culture</title><author>Park, Ji-young ; Lee, Eun-Sook ; Amna, Touseef ; Jang, Yeonju ; Park, Dong Hyup ; Kim, Byoung-Suhk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-118e67fb95d0e96f70752805858c691458c0768653fa7280622598609d4449a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Biocomposite</topic><topic>Biotechnology</topic><topic>Carbonates</topic><topic>Cell culture</topic><topic>Electrospinning</topic><topic>Heat treatment</topic><topic>Mechanical properties</topic><topic>Mechanical property</topic><topic>Morphology</topic><topic>Nanofiber</topic><topic>Nanofibers</topic><topic>Nanostructure</topic><topic>Poly(propylene carbonate)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Ji-young</creatorcontrib><creatorcontrib>Lee, Eun-Sook</creatorcontrib><creatorcontrib>Amna, Touseef</creatorcontrib><creatorcontrib>Jang, Yeonju</creatorcontrib><creatorcontrib>Park, Dong Hyup</creatorcontrib><creatorcontrib>Kim, Byoung-Suhk</creatorcontrib><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Biotechnology Research Abstracts</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Colloids and surfaces. A, Physicochemical and engineering aspects</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Ji-young</au><au>Lee, Eun-Sook</au><au>Amna, Touseef</au><au>Jang, Yeonju</au><au>Park, Dong Hyup</au><au>Kim, Byoung-Suhk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of heat-treatment on surface morphologies, mechanical properties of nanofibrous poly(propylene carbonate) biocomposites and its cell culture</atitle><jtitle>Colloids and surfaces. A, Physicochemical and engineering aspects</jtitle><date>2016-03-05</date><risdate>2016</risdate><volume>492</volume><spage>138</spage><epage>143</epage><pages>138-143</pages><issn>0927-7757</issn><eissn>1873-4359</eissn><abstract>[Display omitted]
•PPC nanofibers exhibited soft rubber-like features.•Mechanics of PPC nanofibers were dramatically improved after heat-treatment.•PPC/PLA composite nanofibers showed topographically peculiar morphologies.•Biomedical applications as a scaffold tissue engineering.
We report controlled surface morphologies, mechanical properties and cell culture of biomimetic pure poly(propylene carbonate) (PPC) and PPC/poly(lactic acid) (PLA) composite nanofibers prepared by sol–gel electrospinning. Pure PPC nanofibers exhibited soft rubber-like features with lower mechanical properties (elastic modulus ∼59.7MPa, tensile strength ∼6.2MPa), while the mechanical properties of as-spun PPC nanofibers were dramatically improved after heat-treatments at 60°C. Furthermore, the PPC/PLA composite nanofibers exhibited topographically peculiar morphologies (in particular, an embossing-like surface protrusions), probably due to poor miscibility between PPC and PLA. CCK-8 assay results of cultured myoblasts clarified that pure PPC and PPC/PLA composite nanofibers were nontoxic to the cells, which therefore, suggest them to be used in biomedical applications as a scaffold for tissue engineering.</abstract><pub>Elsevier B.V</pub><doi>10.1016/j.colsurfa.2015.11.075</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0927-7757 |
| ispartof | Colloids and surfaces. A, Physicochemical and engineering aspects, 2016-03, Vol.492, p.138-143 |
| issn | 0927-7757 1873-4359 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1837295166 |
| source | ScienceDirect Journals (5 years ago - present) |
| subjects | Biocomposite Biotechnology Carbonates Cell culture Electrospinning Heat treatment Mechanical properties Mechanical property Morphology Nanofiber Nanofibers Nanostructure Poly(propylene carbonate) |
| title | Effects of heat-treatment on surface morphologies, mechanical properties of nanofibrous poly(propylene carbonate) biocomposites and its cell culture |
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