Magnetic bead-based proteomic technology to study paricalcitol effect in kidney transplant recipients

Secondary hyperparathyroidism is a common complication in patients with chronic kidney disease and frequently persists after kidney transplantation. Paricalcitol, a selective vitamin D receptor activator, is indicated in the management of this disorder and recent evidences have suggested that this d...

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Veröffentlicht in:	European journal of pharmacology 2013-06, Vol.709 (1-3), p.72-79
Hauptverfasser:	Pérez, Vanessa, Sánchez-Escuredo, Anna, Lauzurica, Ricardo, Bayés, Beatriu, Navarro-Muñoz, Maribel, Pastor, María Cruz, Cañas, Laura, Bonet, Josep, Romero, Ramón
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged alkaline phosphatase Biomarkers - blood Biomarkers - chemistry bone density Bone Density - drug effects Bone Density Conservation Agents - therapeutic use Bone Resorption - etiology Bone Resorption - prevention & control Bradykinin Bradykinin - blood Bradykinin - chemistry complement Complement C4 Complement C4 - analysis Complement C4 - chemistry drugs Ergocalciferols - therapeutic use Female glomerular filtration rate Humans hyperparathyroidism Hyperparathyroidism, Secondary - blood Hyperparathyroidism, Secondary - drug therapy Hyperparathyroidism, Secondary - etiology Hyperparathyroidism, Secondary - physiopathology Kidney - drug effects Kidney - immunology Kidney - physiopathology kidney diseases Kidney Failure, Chronic - immunology Kidney Failure, Chronic - physiopathology Kidney Failure, Chronic - therapy kidney transplant Kidney transplantation Kidney Transplantation - immunology Magnetic Phenomena Male matrix-assisted laser desorption-ionization mass spectrometry Microspheres Middle Aged parathyroid hormone Paricalcitol patients Peptide Fragments - blood Peptide Fragments - chemistry Plasma peptidome Proteomics Proteomics - methods Receptors, Calcitriol - agonists Receptors, Calcitriol - metabolism Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization vitamin D
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