Taurine Pretreatment Prevents Isoflurane-Induced Cognitive Impairment by Inhibiting ER Stress-Mediated Activation of Apoptosis Pathways in the Hippocampus in Aged Rats

Isoflurane, a commonly used inhalation anesthetic, may induce neurocognitive deficits, especially in elderly patients after surgery. Recent study demonstrated that isoflurane caused endoplasmic reticulum (ER) stress and subsequent neuronal apoptosis in the brain, contributing to cognitive deficits....

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Veröffentlicht in:Neurochemical research 2016-10, Vol.41 (10), p.2517-2525
Hauptverfasser: Zhang, Yanan, Li, Dongliang, Li, Haiou, Hou, Dailiang, Hou, Jingdong
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Sprache:eng
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