Value of combined measurement of intestinal fatty acid-binding protein and fecal calprotectin in diagnosis of necrotizing enterocolitis in full-term neonates
To study the value of combined measurement of intestinal fatty acid-binding protein (I-FABP) and fecal calprotectin (FC) in the diagnosis of necrotizing enterocolitis (NEC) in full-term neonates. A total of 36 full-term neonates with NEC (case group) and 39 neonates without digestive system diseases...
Gespeichert in:
| Veröffentlicht in: | Zhongguo dang dai er ke za zhi 2016-11, Vol.18 (11), p.1080-1083 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | chi |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1083 |
|---|---|
| container_issue | 11 |
| container_start_page | 1080 |
| container_title | Zhongguo dang dai er ke za zhi |
| container_volume | 18 |
| creator | Tian, Yun-Fen Li, Li Mi, Hong-Ying Huang-Pu, Chun-Rong He, Shan Xu, Xiao-Yan Cao, Yong-Jiu |
| description | To study the value of combined measurement of intestinal fatty acid-binding protein (I-FABP) and fecal calprotectin (FC) in the diagnosis of necrotizing enterocolitis (NEC) in full-term neonates.
A total of 36 full-term neonates with NEC (case group) and 39 neonates without digestive system diseases (control group) were enrolled as study subjects. ELISA was used to measure the serum I-FABP level and fecal FC level, and the clinical value of I-FABP combined with FC in the diagnosis of NEC was evaluated.
The case group had significantly higher I-FABP and FC levels than the control group (P |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1837030193</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1837030193</sourcerecordid><originalsourceid>FETCH-LOGICAL-p569-1b542b7bd865944d36a050526cae24dcdf8a12dacd0ab2c01cc5c9086ae1f2133</originalsourceid><addsrcrecordid>eNo1kMtOwzAQRbMA0VL4BeQlm0h2HCfOElW8pEpsKrbRxB5XRo5T4mRR_oV_ZQJlYVm6c-6dx0W2FpzrXGvJV9l1Sh-cK1028ipbFbUWdV016-z7HcKMbHDMDH3nI1rWI6R5xB7jtOg-TpgmHyEwB9N0YmC8zQm1Ph7YcRwm9JFBtMyhIYjer2jIQ2ZmPRzikHxawiIaqvmvxUr5OA5mCH6iIpFuDiEnrSdsiEBtb7JLByHh7fnfZPunx_32Jd-9Pb9uH3b5UVVNLjpVFl3dWV2ppiytrIArrorKABalNdZpEIUFYzl0heHCGGUaritA4Qoh5Sa7_4ulwT9n2rbtfTIYAtAgc2qFljWXXDQLendG565H2x5H38N4av8vKn8A64l13w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1837030193</pqid></control><display><type>article</type><title>Value of combined measurement of intestinal fatty acid-binding protein and fecal calprotectin in diagnosis of necrotizing enterocolitis in full-term neonates</title><source>PubMed Central (Open access)</source><source>MEDLINE</source><source>EZB Electronic Journals Library</source><creator>Tian, Yun-Fen ; Li, Li ; Mi, Hong-Ying ; Huang-Pu, Chun-Rong ; He, Shan ; Xu, Xiao-Yan ; Cao, Yong-Jiu</creator><creatorcontrib>Tian, Yun-Fen ; Li, Li ; Mi, Hong-Ying ; Huang-Pu, Chun-Rong ; He, Shan ; Xu, Xiao-Yan ; Cao, Yong-Jiu</creatorcontrib><description>To study the value of combined measurement of intestinal fatty acid-binding protein (I-FABP) and fecal calprotectin (FC) in the diagnosis of necrotizing enterocolitis (NEC) in full-term neonates.
A total of 36 full-term neonates with NEC (case group) and 39 neonates without digestive system diseases (control group) were enrolled as study subjects. ELISA was used to measure the serum I-FABP level and fecal FC level, and the clinical value of I-FABP combined with FC in the diagnosis of NEC was evaluated.
The case group had significantly higher I-FABP and FC levels than the control group (P<0.05). In the case group, serum I-FABP level was positively correlated with fecal FC level (r=0.71, P<0.05). In the diagnosis of NEC, I-FABP alone, FC alone, and I-FABP/FC combination had sensitivities of 83.3%, 81.5%, and 79.5%, specificities of 72.5%, 75.8%, and 86.3%, and areas under the ROC curve (AUCs) of 0.82, 0.81, and 0.88. The combined measurement showed significantly higher specificity and AUC than single measuremen</description><identifier>ISSN: 1008-8830</identifier><identifier>PMID: 27817769</identifier><language>chi</language><publisher>China</publisher><subject>Enterocolitis, Necrotizing - diagnosis ; Fatty Acid-Binding Proteins - blood ; Feces - chemistry ; Female ; Humans ; Infant, Newborn ; Leukocyte L1 Antigen Complex - analysis ; Male</subject><ispartof>Zhongguo dang dai er ke za zhi, 2016-11, Vol.18 (11), p.1080-1083</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27817769$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tian, Yun-Fen</creatorcontrib><creatorcontrib>Li, Li</creatorcontrib><creatorcontrib>Mi, Hong-Ying</creatorcontrib><creatorcontrib>Huang-Pu, Chun-Rong</creatorcontrib><creatorcontrib>He, Shan</creatorcontrib><creatorcontrib>Xu, Xiao-Yan</creatorcontrib><creatorcontrib>Cao, Yong-Jiu</creatorcontrib><title>Value of combined measurement of intestinal fatty acid-binding protein and fecal calprotectin in diagnosis of necrotizing enterocolitis in full-term neonates</title><title>Zhongguo dang dai er ke za zhi</title><addtitle>Zhongguo Dang Dai Er Ke Za Zhi</addtitle><description>To study the value of combined measurement of intestinal fatty acid-binding protein (I-FABP) and fecal calprotectin (FC) in the diagnosis of necrotizing enterocolitis (NEC) in full-term neonates.
A total of 36 full-term neonates with NEC (case group) and 39 neonates without digestive system diseases (control group) were enrolled as study subjects. ELISA was used to measure the serum I-FABP level and fecal FC level, and the clinical value of I-FABP combined with FC in the diagnosis of NEC was evaluated.
The case group had significantly higher I-FABP and FC levels than the control group (P<0.05). In the case group, serum I-FABP level was positively correlated with fecal FC level (r=0.71, P<0.05). In the diagnosis of NEC, I-FABP alone, FC alone, and I-FABP/FC combination had sensitivities of 83.3%, 81.5%, and 79.5%, specificities of 72.5%, 75.8%, and 86.3%, and areas under the ROC curve (AUCs) of 0.82, 0.81, and 0.88. The combined measurement showed significantly higher specificity and AUC than single measuremen</description><subject>Enterocolitis, Necrotizing - diagnosis</subject><subject>Fatty Acid-Binding Proteins - blood</subject><subject>Feces - chemistry</subject><subject>Female</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Leukocyte L1 Antigen Complex - analysis</subject><subject>Male</subject><issn>1008-8830</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kMtOwzAQRbMA0VL4BeQlm0h2HCfOElW8pEpsKrbRxB5XRo5T4mRR_oV_ZQJlYVm6c-6dx0W2FpzrXGvJV9l1Sh-cK1028ipbFbUWdV016-z7HcKMbHDMDH3nI1rWI6R5xB7jtOg-TpgmHyEwB9N0YmC8zQm1Ph7YcRwm9JFBtMyhIYjer2jIQ2ZmPRzikHxawiIaqvmvxUr5OA5mCH6iIpFuDiEnrSdsiEBtb7JLByHh7fnfZPunx_32Jd-9Pb9uH3b5UVVNLjpVFl3dWV2ppiytrIArrorKABalNdZpEIUFYzl0heHCGGUaritA4Qoh5Sa7_4ulwT9n2rbtfTIYAtAgc2qFljWXXDQLendG565H2x5H38N4av8vKn8A64l13w</recordid><startdate>201611</startdate><enddate>201611</enddate><creator>Tian, Yun-Fen</creator><creator>Li, Li</creator><creator>Mi, Hong-Ying</creator><creator>Huang-Pu, Chun-Rong</creator><creator>He, Shan</creator><creator>Xu, Xiao-Yan</creator><creator>Cao, Yong-Jiu</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201611</creationdate><title>Value of combined measurement of intestinal fatty acid-binding protein and fecal calprotectin in diagnosis of necrotizing enterocolitis in full-term neonates</title><author>Tian, Yun-Fen ; Li, Li ; Mi, Hong-Ying ; Huang-Pu, Chun-Rong ; He, Shan ; Xu, Xiao-Yan ; Cao, Yong-Jiu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p569-1b542b7bd865944d36a050526cae24dcdf8a12dacd0ab2c01cc5c9086ae1f2133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2016</creationdate><topic>Enterocolitis, Necrotizing - diagnosis</topic><topic>Fatty Acid-Binding Proteins - blood</topic><topic>Feces - chemistry</topic><topic>Female</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Leukocyte L1 Antigen Complex - analysis</topic><topic>Male</topic><toplevel>online_resources</toplevel><creatorcontrib>Tian, Yun-Fen</creatorcontrib><creatorcontrib>Li, Li</creatorcontrib><creatorcontrib>Mi, Hong-Ying</creatorcontrib><creatorcontrib>Huang-Pu, Chun-Rong</creatorcontrib><creatorcontrib>He, Shan</creatorcontrib><creatorcontrib>Xu, Xiao-Yan</creatorcontrib><creatorcontrib>Cao, Yong-Jiu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Zhongguo dang dai er ke za zhi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tian, Yun-Fen</au><au>Li, Li</au><au>Mi, Hong-Ying</au><au>Huang-Pu, Chun-Rong</au><au>He, Shan</au><au>Xu, Xiao-Yan</au><au>Cao, Yong-Jiu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Value of combined measurement of intestinal fatty acid-binding protein and fecal calprotectin in diagnosis of necrotizing enterocolitis in full-term neonates</atitle><jtitle>Zhongguo dang dai er ke za zhi</jtitle><addtitle>Zhongguo Dang Dai Er Ke Za Zhi</addtitle><date>2016-11</date><risdate>2016</risdate><volume>18</volume><issue>11</issue><spage>1080</spage><epage>1083</epage><pages>1080-1083</pages><issn>1008-8830</issn><abstract>To study the value of combined measurement of intestinal fatty acid-binding protein (I-FABP) and fecal calprotectin (FC) in the diagnosis of necrotizing enterocolitis (NEC) in full-term neonates.
A total of 36 full-term neonates with NEC (case group) and 39 neonates without digestive system diseases (control group) were enrolled as study subjects. ELISA was used to measure the serum I-FABP level and fecal FC level, and the clinical value of I-FABP combined with FC in the diagnosis of NEC was evaluated.
The case group had significantly higher I-FABP and FC levels than the control group (P<0.05). In the case group, serum I-FABP level was positively correlated with fecal FC level (r=0.71, P<0.05). In the diagnosis of NEC, I-FABP alone, FC alone, and I-FABP/FC combination had sensitivities of 83.3%, 81.5%, and 79.5%, specificities of 72.5%, 75.8%, and 86.3%, and areas under the ROC curve (AUCs) of 0.82, 0.81, and 0.88. The combined measurement showed significantly higher specificity and AUC than single measuremen</abstract><cop>China</cop><pmid>27817769</pmid><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1008-8830 |
| ispartof | Zhongguo dang dai er ke za zhi, 2016-11, Vol.18 (11), p.1080-1083 |
| issn | 1008-8830 |
| language | chi |
| recordid | cdi_proquest_miscellaneous_1837030193 |
| source | PubMed Central (Open access); MEDLINE; EZB Electronic Journals Library |
| subjects | Enterocolitis, Necrotizing - diagnosis Fatty Acid-Binding Proteins - blood Feces - chemistry Female Humans Infant, Newborn Leukocyte L1 Antigen Complex - analysis Male |
| title | Value of combined measurement of intestinal fatty acid-binding protein and fecal calprotectin in diagnosis of necrotizing enterocolitis in full-term neonates |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T16%3A29%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Value%20of%20combined%20measurement%20of%20intestinal%20fatty%20acid-binding%20protein%20and%20fecal%20calprotectin%20in%20diagnosis%20of%20necrotizing%20enterocolitis%20in%20full-term%20neonates&rft.jtitle=Zhongguo%20dang%20dai%20er%20ke%20za%20zhi&rft.au=Tian,%20Yun-Fen&rft.date=2016-11&rft.volume=18&rft.issue=11&rft.spage=1080&rft.epage=1083&rft.pages=1080-1083&rft.issn=1008-8830&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1837030193%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1837030193&rft_id=info:pmid/27817769&rfr_iscdi=true |