Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal carcinoma: a phase 3, multicentre, randomised controlled trial

Summary Background The value of adding cisplatin, fluorouracil, and docetaxel (TPF) induction chemotherapy to concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma is unclear. We aimed to compare TPF induction chemotherapy plus concurrent chemoradiotherapy with concurrent...

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Veröffentlicht in:	The lancet oncology 2016-11, Vol.17 (11), p.1509-1520
Hauptverfasser:	Sun, Ying, Prof, Li, Wen-Fei, MD, Chen, Nian-Yong, Prof, Zhang, Ning, Prof, Hu, Guo-Qing, Prof, Xie, Fang-Yun, Prof, Sun, Yan, Prof, Chen, Xiao-Zhong, Prof, Li, Jin-Gao, Prof, Zhu, Xiao-Dong, Prof, Hu, Chao-Su, Prof, Xu, Xiang-Ying, Prof, Chen, Yuan-Yuan, MD, Hu, Wei-Han, Prof, Guo, Ling, Prof, Mo, Hao-Yuan, Prof, Chen, Lei, MD, Mao, Yan-Ping, MD, Sun, Rui, MD, Ai, Ping, MD, Liang, Shao-Bo, MD, Long, Guo-Xian, MD, Zheng, Bao-Min, MD, Feng, Xing-Lai, MD, Gong, Xiao-Chang, MD, Li, Ling, MD, Shen, Chun-Ying, MD, Xu, Jian-Yu, MD, Guo, Ying, PhD, Chen, Yu-Ming, Prof, Zhang, Fan, MD, Lin, Li, MD, Tang, Ling-Long, MD, Liu, Meng-Zhong, Prof, Ma, Jun, Dr Prof
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Carcinoma Chemoradiotherapy - adverse effects Chemotherapy Cisplatin - administration & dosage Docetaxel Female Fluorouracil - administration & dosage Head & neck cancer Hematology Hematology, Oncology and Palliative Medicine Humans Induction Chemotherapy - adverse effects Male Medical prognosis Metastasis Middle Aged Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms - mortality Nasopharyngeal Neoplasms - therapy Neutropenia Radiation therapy Studies Taxoids - administration & dosage
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