Lipoic acid protects gastric mucosa from ethanol-induced injury in rat through a mechanism involving aldehyde dehydrogenase 2 activation

Abstract Numerous studies demonstrate that reactive aldehydes are highly toxic and aldehyde dehydrogenase 2 (ALDH2)-mediated detoxification of reactive aldehydes is thought as an endogenous protective mechanism against reactive aldehydes-induced cell injury. This study aims to explore whether lipoic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Alcohol (Fayetteville, N.Y.) N.Y.), 2016-11, Vol.56, p.21-28
Hauptverfasser:	Li, Jia-Hui, Ju, Gui-Xia, Jiang, Jun-lin, Li, Nian-Sheng, Peng, Jun, Luo, Xiu-Ju
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Hydroxy-2-nonenal Acids Alcohol Aldehyde dehydrogenase 2 Aldehyde Dehydrogenase, Mitochondrial - metabolism Animals Antioxidants Dehydrogenases Drug dosages Enzyme Activation - drug effects Enzyme Activation - physiology Ethanol Ethanol - toxicity Experiments Gastric mucosa Gastric Mucosa - drug effects Gastric Mucosa - enzymology Gastric Mucosa - pathology Laboratory animals Lipid peroxidation Lipids Lipoic acid Male Mucous membrane Psychiatry Random Allocation Rats Rats, Sprague-Dawley Studies Thioctic Acid - pharmacology Ulcers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!