Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-analysis

BACKGROUND—The association of genetic polymorphisms and clopidogrel efficacy in patients with ischemic stroke or transient ischemic attack (TIA) remains controversial. We performed a systematic review and meta-analysis to assess the association between genetic polymorphisms, especially CYP2C19 genot...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2017-01, Vol.135 (1), p.21-33
Hauptverfasser:	Pan, Yuesong, Chen, Weiqi, Xu, Yun, Yi, Xingyang, Han, Yan, Yang, Qingwu, Li, Xin, Huang, Li’an, Johnston, S Claiborne, Zhao, Xingquan, Liu, Liping, Zhang, Qi, Wang, Guangyao, Wang, Yongjun, Wang, Yilong
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Cytochrome P-450 CYP2C19 - genetics Databases, Factual Genotype Humans Ischemic Attack, Transient - drug therapy Ischemic Attack, Transient - genetics Ischemic Attack, Transient - pathology Polymorphism, Genetic Risk Stroke - drug therapy Stroke - genetics Stroke - pathology Ticlopidine - analogs & derivatives Ticlopidine - therapeutic use
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