Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B

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Veröffentlicht in:	Journal of hepatology 2017-02, Vol.66 (2), p.275-281
Hauptverfasser:	Lai, Ching-Lung, Wong, Danny, Ip, Philip, Kopaniszen, Malgorzata, Seto, Wai-Kay, Fung, James, Huang, Fung-Yu, Lee, Brian, Cullaro, Giuseppe, Chong, Chun Kong, Wu, Ringo, Cheng, Charles, Yuen, John, Ngai, Vincent, Yuen, Man-Fung
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - administration & dosage Adenine - analogs & derivatives Adenine - pharmacokinetics Antiviral Agents - administration & dosage Antiviral Agents - pharmacokinetics Antiviral therapy Biopsy Biopsy - methods Circular DNA Clinical trials Deoxyribonucleic acid DNA DNA, Circular - analysis DNA, Viral - blood Female Gastroenterology and Hepatology Hepatitis Hepatitis B Hepatitis B surface antigen Hepatitis B virus Hepatitis B virus - drug effects Hepatitis B virus - genetics Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - virology Hepatocytes Humans Lamivudine - administration & dosage Lamivudine - pharmacokinetics Liver - pathology Liver - virology Liver biopsy Male Middle Aged Nucleosides - pharmacology Organophosphonates - administration & dosage Organophosphonates - pharmacokinetics Outcome Assessment (Health Care) Patients Replication Ribonucleic acid RNA Thymidine - administration & dosage Thymidine - analogs & derivatives Thymidine - pharmacokinetics Time Virus replication Virus Replication - drug effects
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