The role of variants regulating metformin transport and action in women with polycystic ovary syndrome

Variants in genes encoding metformin transport proteins and the gene are associated with metformin response. We hypothesized that these gene variants contribute to variable metformin treatment response in polycystic ovary syndrome. The discovery cohort (n = 38) was studied in an open-label study. Re...

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Veröffentlicht in:	Pharmacogenomics 2016-11, Vol.17 (16), p.1765-1773
Hauptverfasser:	Pau, Cindy T, Cheang, Kai I, Modi, Bhavi P, Kasippillai, Thushiga, Keefe, Candace C, Shulleeta, Maria, Evans, William S, Pal, Lubna, Strauss, Jerome F, Nestler, John E, Welt, Corrine K
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiabetics Ataxia telangiectasia mutated protein Genomics Genotypes Glucose insulin Insulin resistance Kinases MATE Metformin OCT Polycystic ovary syndrome Testosterone
Online-Zugang:	Volltext
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