Discovery of Rigidified α,β-Unsaturated Imines as New Resistance-breaking Insecticides for Malaria Vector Control

During our continuous search for new resistance-breaking insecticides applicable to malaria vector control, a new class of α,β-unsaturated imines was identified by applying the principle of conformational rigidification as a powerful tool for compound optimisation. Herein we describe the successful...

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Veröffentlicht in:	Chimia 2016-10, Vol.70 (10), p.694-697
Hauptverfasser:	Arlt, Alexander, Böhnke, Niels, Horstmann, Sebastian, Vermeer, Arnoldus W P, Werner, Stefan, Velten, Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drug Discovery Imines - pharmacology Insect Vectors Insecticide Resistance Insecticides - chemical synthesis Insecticides - pharmacology Malaria - prevention & control Mosquito Control - methods
Online-Zugang:	Volltext
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