In situ diselenide-crosslinked polymeric micelles for ROS-mediated anticancer drug delivery

Abstract Stimuli-responsive micelles have emerged as the drug carrier for cancer therapy since they can exclusively release the drug via their structural changes in response to the specific stimuli of the target site. Herein, we developed the in situ diselenide-crosslinked micelles (DCMs), which are...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomaterials 2016-10, Vol.103, p.56-66
Hauptverfasser:	Deepagan, V.G, Kwon, Seunglee, You, Dong Gil, Nguyen, Van Quy, Um, Wooram, Ko, Hyewon, Lee, Hansang, Jo, Dong-Gyu, Kang, Young Mo, Park, Jae Hyung
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Antibiotics, Antineoplastic - administration & dosage Antibiotics, Antineoplastic - chemistry Biostability Carriers Cell Line, Tumor Cross-Linking Reagents - chemistry Dentistry Derivatives Diselenide bond Doxorubicin - administration & dosage Doxorubicin - chemistry Drug delivery Drug delivery systems Drug Stability Drugs Emulsions - chemistry Humans In situ crosslinking Male Mice Mice, Nude Micelles Molecular Targeted Therapy - methods Nanocapsules - administration & dosage Nanocapsules - chemistry Nanocapsules - ultrastructure Neoplasms, Experimental - chemistry Neoplasms, Experimental - drug therapy Particle Size Polyethylene glycol Polyethylene Glycols - chemistry Polymeric micelle Reactive Oxygen Species - chemistry ROS-responsive release Selenium - chemistry Therapy Treatment Outcome Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!