Hyperspectral backscatter imaging: a label-free approach to cytogenetics

Current techniques for chromosome analysis need to be improved for rapid, economical identification of complex chromosomal defects by sensitive and selective visualisation. In this paper, we present a straightforward method for characterising unstained human metaphase chromosomes. Backscatter imagin...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2016-08, Vol.408 (21), p.5701-5709
Hauptverfasser:	Rebner, Karsten, Ostertag, Edwin, Kessler, Rudolf W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Backscattering Biochemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chromosomes Chromosomes - chemistry Chromosomes - ultrastructure Cost analysis Cytogenetic Analysis - methods Cytogenetics Data analysis Fine structure Food Science Genetic research Humans Imaging Infrared spectroscopy Laboratory Medicine Light Mathematical analysis Metaphase Methods Microscopy Microscopy - methods Monitoring/Environmental Analysis Monitors Morphology Optical Imaging - methods Process controls Research Paper Scattering Spectral Karyotyping - methods Spectroscopy, Near-Infrared - methods Spectrum analysis
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