Antisense precision polymer micelles require less poly(ethylenimine) for efficient gene knockdown

Therapeutic nucleic acids are powerful molecules for shutting down protein expression. However, their cellular uptake is poor and requires transport vectors, such as cationic polymers. Of these, poly(ethylenimine) (PEI) has been shown to be an efficient vehicle for nucleic acid transport into cells....

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Veröffentlicht in:Nanoscale 2015-12, Vol.7 (48), p.20625-20634
Hauptverfasser: Fakhoury, Johans J, Edwardson, Thomas G, Conway, Justin W, Trinh, Tuan, Khan, Farhad, Barłóg, Maciej, Bazzi, Hassan S, Sleiman, Hanadi F
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Sprache:eng
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