A ratiometric fluorescence RRE RNA-targeted assay for a new fluorescence ligand

The Rev protein regulates HIV-1 gene expression. Small ligands that bind to the Rev response element (RRE) RNA would inhibit Rev function and suppress HIV-1 replication. A novel ratiometric fluorescence assay was applied in the present study to monitor ligand-RNA interactions by using red-emitting C...

Ausführliche Beschreibung