Delivering Nucleic-Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives

As well as acting to fill defects and allow for cell infiltration and proliferation in regenerative medicine, biomaterial scaffolds can also act as carriers for therapeutics, further enhancing their efficacy. Drug and protein delivery on scaffolds have shown potential, however, supraphysiological qu...

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Veröffentlicht in:	Advanced materials (Weinheim) 2016-07, Vol.28 (27), p.5447-5469
Hauptverfasser:	Raftery, Rosanne M., Walsh, David P., Castaño, Irene Mencía, Heise, Andreas, Duffy, Garry P., Cryan, Sally-Ann, O'Brien, Fergal J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomaterials Biomedical materials Gene therapy gene-activated scaffolds Nanostructure non-viral gene therapy orthopedic tissue engineering Proteins RNAi Scaffolds Surgical implants Tissue engineering
Online-Zugang:	Volltext
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