Oxymatrine attenuated isoproterenol-induced heart failure in rats via regulation of COX-2/PGI2 pathway

Abstract Oxymatrine (OMT) is an active constituent of traditional Chinese herb Sophora japonica Ait which has been shown to exert potent anti-inflammatory,anti-oxidant and anti-fibrosis properties. Our previous studies have demonstrated that OMT has protective effects on isoproterenol-induced heart...

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Veröffentlicht in:Biomedicine & pharmacotherapy 2016-12, Vol.84, p.1359-1366
Hauptverfasser: Zhou, Ru, Xu, Qingbin, Xu, Yehua, Xiong, Aiqin, Wang, Yang, Ma, Ping
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Sprache:eng
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