Effect of rivaroxaban on prothrombin fragment 1 + 2 compared with warfarin in patients with acute cardioembolic stroke: Insight from its serial measurement

Abstract Introduction Patients with intracerebral hemorrhage during rivaroxaban treatment have small hematoma and favorable outcomes compared with those with warfarin. We investigated its possible mechanism, focusing on prothrombin fragment 1 + 2 (F1 + 2), a marker of thrombin generation. Materials...

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Veröffentlicht in:	Thrombosis research 2016-12, Vol.148, p.9-14
Hauptverfasser:	Hagii, Joji, Tomita, Hirofumi, Metoki, Norifumi, Tamai, Yoshiko, Saito, Shin, Shiroto, Hiroshi, Hitomi, Hiroyasu, Kamada, Takaatsu, Seino, Satoshi, Takahashi, Koki, Sasaki, Satoko, Yasujima, Minoru, Okumura, Ken
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Aged Aged, 80 and over Anticoagulants - therapeutic use Bleeding Cerebral Hemorrhage - blood Cerebral Hemorrhage - complications Cerebral Hemorrhage - drug therapy Factor Xa Inhibitors - blood Factor Xa Inhibitors - therapeutic use Female Fibrin Fibrinogen Degradation Products - analysis Hematology, Oncology and Palliative Medicine Hemorrhage Humans Male Peptide Fragments - blood Prothrombin Prothrombin fragment 1 + 2 Prothrombin Time Rivaroxaban Rivaroxaban - blood Rivaroxaban - therapeutic use Stroke Stroke - blood Stroke - complications Stroke - drug therapy Warfarin Warfarin - therapeutic use
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