DiffusionKit: A light one-stop solution for diffusion MRI data analysis

•DiffusionKit has a full pipeline for (pre-)processing and visualization of diffusion MRI data.•DiffusionKit has cross-platform support and a small installation size without 3rd party dependency.•DiffusionKit has both a GUI interface and command-line functions that enable easy operation and batch pr...

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Veröffentlicht in:Journal of neuroscience methods 2016-11, Vol.273, p.107-119
Hauptverfasser: Xie, Sangma, Chen, Liangfu, Zuo, Nianming, Jiang, Tianzi
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container_end_page 119
container_issue
container_start_page 107
container_title Journal of neuroscience methods
container_volume 273
creator Xie, Sangma
Chen, Liangfu
Zuo, Nianming
Jiang, Tianzi
description •DiffusionKit has a full pipeline for (pre-)processing and visualization of diffusion MRI data.•DiffusionKit has cross-platform support and a small installation size without 3rd party dependency.•DiffusionKit has both a GUI interface and command-line functions that enable easy operation and batch processing. Diffusion magnetic resonance imaging (dMRI) techniques are receiving increasing attention due to their ability to characterize the arrangement map of white matter in vivo. However, the existing toolkits for dMRI analysis that have accompanied this surge possess noticeable limitations, such as large installation size, an incomplete pipeline, and a lack of cross-platform support. In this work, we developed a light, one-stop, cross-platform solution for dMRI data analysis, called DiffusionKit. It delivers a complete pipeline, including data format conversion, dMRI preprocessing, local reconstruction, white matter fiber tracking, fiber statistical analyses and various visualization schemes. Furthermore, DiffusionKit is a self-contained executable toolkit, without the need to install any other software. The DiffusionKit package is implemented in C/C++ and Qt/VTK, is freely available at http://diffusion.brainnetome.org and https://www.nitrc.org/projects/diffusionkit. The website of DiffusionKit includes test data, a complete tutorial and a series of tutorial examples. A mailing list has also been established for update notification and questions and answers. DiffusionKit provides a full-function pipeline for dMRI data analysis, including data processing, modeling and visualization. Additionally, it provides both a graphical user interface (GUI) and command-line functions, which are helpful for batch processing. The standalone installation package has a small size and cross-platform support. DiffusionKit provides a complete pipeline with cutting-edge methods for dMRI data analysis, including both a GUI interface and command-line functions. The rich functions for both data analysis and visualization will facilitate and benefit dMRI research.
doi_str_mv 10.1016/j.jneumeth.2016.08.011
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subjects Algorithms
Anatomical connectivity
Anisotropy
Brain - diagnostic imaging
Connectome
Diffusion Magnetic Resonance Imaging
Diffusion MRI
DiffusionKit
DTI
HARDI
Humans
Image Processing, Computer-Assisted
Models, Neurological
Nerve Fibers, Myelinated - physiology
White Matter - diagnostic imaging
title DiffusionKit: A light one-stop solution for diffusion MRI data analysis
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