Direct inhibition by a statin of TNFalpha-induced leukocyte recruitment in rat pial venules - in vivo confocal microscopic study

3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been shown to block leukocyte-endothelial interaction independently of their cholesterol-lowering properties. The effects of statins are generally attributed to a decrease in mevalonate caused by inhibition of HMG-Co...

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Veröffentlicht in:	Pathophysiology (Amsterdam) 2004-10, Vol.11 (2), p.121-128
Hauptverfasser:	Obama, Ruriko, Ishida, Hideyuki, Takizawa, Shunya, Tsuji, Chizuko, Nakazawa, Hiroe, Shinohara, Yukito
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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