Rolipram, a specific type IV phosphodiesterase inhibitor, ameliorates indomethacin-induced gastric mucosal injury in rats

Inhibition of type IV phosphodiesterase activity is beneficial in various inflammation mediated by its function to suppress the production of inflammatory cytokines in inflammatory cells. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin are well known to develop gastric mucosal les...

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Veröffentlicht in:	Pathophysiology (Amsterdam) 2003-05, Vol.9 (3), p.195-200
Hauptverfasser:	Nakamura, Chieko, Otaka, Michiro, Odashima, Masaru, Jin, Mario, Konishi, Noriaki, Horikawa, Youhei, Matsuhashi, Tamotsu, Watanabe, Sumio
Format:	Artikel
Sprache:	eng
Schlagworte:	Mucosal injury Neutrophil NSAIDs Phosphodiesterase inhibitor
Online-Zugang:	Volltext
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